[1]盛雪燕,严兴科,邢家铭,等.针灸治疗干眼症随机对照临床研究文献的Meta分析[J].甘肃中医药大学学报,2015,32(01):56-60.
 SHENG Xueyan,YAN Xingke,XING Jiaming,et al.Meta-analysis on acupuncture for dry eyes based on the clinical literatures: a randomized controlled trial[J].Journal of Gansu University of Chinese Medicine,2015,32(01):56-60.
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针灸治疗干眼症随机对照临床研究文献的Meta分析()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
32卷
期数:
2015年01期
页码:
56-60
栏目:
文献研究
出版日期:
2015-02-25

文章信息/Info

Title:
Meta-analysis on acupuncture for dry eyes based on the clinical literatures: a randomized controlled trial
作者:
盛雪燕 严兴科 邢家铭 韩雅迪
甘肃中医学院针灸推拿学院, 甘肃 兰州 730000
Author(s):
SHENG Xueyan YAN Xingke XING Jiaming HAN Yadi
Acupuncture and Tuina-massage School of Gansu College of TCM, Lanzhou 730000, China
关键词:
针灸干眼症随机对照Meta分析
Keywords:
acupuncturedry eyesrandomized controlledmeta-analysis
分类号:
R246.82
摘要:
目的 评价针灸治疗干眼症的有效性和安全性,分析临床研究的现状。方法 检索万方全文数据库、维普数据库、中国期刊网全文数据库(CNKI)、美国医学文摘数据库(PubMed)、中国生物医学文献数据库(CBM)中关于针刺治疗干眼症的临床文献,纳入针灸治疗干眼症与药物治疗比较的随机对照试验(RCT)和临床对照试验(CCT),按照循证医学系统评价的方法,逐一评价纳入研究的质量,并根据改良后牛津评分系统(Jadad评分)量表对纳入文献进行评分,提取有效数据,采用RevMan 5.2 统计软件进行Meta分析。结果 8篇文献符合纳入标准,共计553例患者。Meta分析显示针灸治疗干眼症与临床药物治疗总有效率比较,差异有统计意义(P<0.05)。结论 针灸治疗干眼症的总有效率优于药物疗法,且无明显不良反应。但鉴于缺乏高质量的随机对照研究支持,且有文献发表偏倚的存在,尚需要更多设计良好的临床随机对照试验来进一步证实其效果。
Abstract:
Objective To assess the evidence of efficacy and safety of acupuncture for dry eyes and analyze the current situation of its clinical setting. Methods The clinical literatures about acupuncture treatment for dry eyes in Wanfang,Chongqing Weipu Database for Chinese Technical Periodicals (VIP),China National Knowledge Infrastructure (CNKI),Pubmed and CBM clinical literature were searched systemically. Randomized controlled trials (RCT) and controlled clinical trials (CCT) that compared the effect of acupuncture for dry eyes with drug treatment were enrolled into the study. The methodological quality of included trials were assessed based on the modified Jadad scale. Valid data were facilitated by using RevMan 5.2. Results 8 trials involving 553 participants satisfied the minimum criteria for meta-analysis. The evidence showed that the overall effective rate of treatment within the group receiving acupuncture was higher than that in drug group,there were statistically significant differences (P<0.05). Conclusion The overall effective rate of acupuncture for dry eyes is significantly superior to drug treatment,and has no obvious adverse reactions. But given the lack of high quality randomized controlled research,and the existence of literature publication bias,it needs more well-designed,randomized controlled clinical trials to confirm the effect.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2014-4-16
基金项目:国家中医药管理局甘肃郑氏针法学术流派传承工作室建设项目(2305135901)。
作者简介:盛雪燕(1988-),女,在读硕士研究生。研究方向:针灸技术规范与临床疗效评价。
通讯作者:严兴科(1974-),男,医学博士,教授。研究方向:针灸调节效应的生物学机制。E-mail: yanxingke@126.com
更新日期/Last Update: 1900-01-01