[1]刘恩远,马蕾.“温通针法”对拟血管性痴呆模型大鼠血浆TXB2、6-keto-PGF1α的含量影响[J].甘肃中医药大学学报,2006,(02):17-19.
 Liu Enyuan,Ma Lei.Effects of Wentong acupuncture method on the contents of TXB2and 6-keto-PGF1α in the serum of model rats with vascular dementia[J].Journal of Gansu University of Chinese Medicine,2006,(02):17-19.
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“温通针法”对拟血管性痴呆模型大鼠血浆TXB2、6-keto-PGF的含量影响()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
期数:
2006年02期
页码:
17-19
栏目:
实验研究
出版日期:
1900-01-01

文章信息/Info

Title:
Effects of Wentong acupuncture method on the contents of TXB2and 6-keto-PGF in the serum of model rats with vascular dementia
作者:
刘恩远 马蕾
甘肃中医学院, 甘肃 兰州 730000
Author(s):
Liu Enyuan Ma Lei
Gansu College Of TCM, 730000, Lanzhou, China
关键词:
温通针法血管性痴呆血栓素B26-酮-前列腺素F
Keywords:
WenTong acupuncture methodvascular dementiaTXB26-keto-PGF
分类号:
R285.5
摘要:
目的:探讨"温通针法"治疗血管性痴呆(VD)的机理,为进一步推广本疗法奠定基础。方法:将60只Wistar大鼠随机分为假手术组、模型对照组、捻转针法组、温通针法组、药物组,采用反复夹闭双侧颈总动脉-再灌注造成血管性痴呆大鼠模型,并行相应处理。各组大鼠经过治疗,跳台实验结束后,利用放射免疫学方法检测大鼠血浆中血栓素B2(TXB2)及6-酮-前列腺素F(6-Keto-PGF)含量。结果:"温通针法"能使VD大鼠血浆中6-Keto-PGF含量显著升高,TXB2含量显著下降。结论:"温通针法"通过调整VD大鼠血浆中TXB2、6-Keto-PGF之间的平衡,增加VD大鼠脑血流量,改善脑功能。这可能是"温通针法"治疗VD取效的主要机制之一。
Abstract:
Objective:To explore the mechanism of Wentong acupuncture method on treating vascular dementia(VD),thereby lay a foundation to further spread the therapy. Methods:60 Wistar rats were randomly divided into negative injury group, model control group, twirling needle method group, Wentong acupuncture method group and medicine group. The VD models of were established by repeated cerebral ischemia-reperfusion of bilateral common carotid artery,and the relevant handling was done.The contents of TXB2 and 6-Keto-PGF in the plasma were examined with radio-immunity method after treating and step-down avoidance test. Results: Wentong acupuncture method could significantly improve the content of 6-Keto-PGF in the plasma and reduce the content of TXB2. Conclusion:Wentong acupuncture method can improve the volume of blood flow in brain of rats with VD and function of by adjust the balance of TXB2 and 6-Keto-PGF.It is possibly one of the main mechanisms of Wentong acupuncture method on treating VD.

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备注/Memo

备注/Memo:
收稿日期:2005-10-28;改回日期:2006-02-21。
作者简介:刘恩远(1978-),男,在读硕士研究生,研究方向:传统针刺手法的临床应用与研究。
更新日期/Last Update: 1900-01-01