[1]王慧,谢波,纪珮,等.中西医结合促排卵治疗多囊卵巢综合征不孕症45例临床观察[J].甘肃中医药大学学报,2016,33(04):52-55.[doi:10.16841/j.issn1003-8450.2016.04.16]
 WANG Hui,XIE Bo,JI Pei,et al.Clinical observation of combined therapy of traditional Chinese and Western medicine by stimulating ovarian in treating 45 cases of infertility induced by polycystic ovarian syndrome[J].Journal of Gansu University of Chinese Medicine,2016,33(04):52-55.[doi:10.16841/j.issn1003-8450.2016.04.16]
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中西医结合促排卵治疗多囊卵巢综合征不孕症45例临床观察()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
33卷
期数:
2016年04期
页码:
52-55
栏目:
临床研究与报道
出版日期:
2016-08-25

文章信息/Info

Title:
Clinical observation of combined therapy of traditional Chinese and Western medicine by stimulating ovarian in treating 45 cases of infertility induced by polycystic ovarian syndrome
作者:
王慧 谢波 纪珮 徐丹
广东省第二中医院妇科, 广东 广州 510095
Author(s):
WANG Hui XIE Bo JI Pei XU Dan
Gynecological Department of Guangdong Second TCM Hospital, Guangzhou, Guangdong, 510095, China
关键词:
多囊卵巢综合征不孕症中西医结合临床观察
Keywords:
polycystic ovarian syndromeinfertilitycombined traditional Chinese and Western medicineclinical observation
分类号:
R271.14
DOI:
10.16841/j.issn1003-8450.2016.04.16
摘要:
目的 观察中西医结合促排卵治疗多囊卵巢综合征(PCOS)不孕症的临床疗效。方法 将90例PCOS不孕症患者随机分为2组,各45例。对照组采用克罗米芬+人绒毛促性腺激素(CC/HCG)治疗,治疗组在对照组治疗方法的基础上加用中药治疗,比较治疗前后2组患者的促黄体生成素(LH)、促卵泡刺激素(FSH)、睾酮(T)、雌二醇(E2)水平及治疗后排卵和妊娠情况。结果 治疗后2组LH水平较治疗前显著降低,差异有统计意义(P<0.05或P<0.01),且治疗组显著低于对照组(P<0.05);治疗组T水平及LH/FSH值较治疗前显著降低,差异有统计意义(P<0.05或P<0.01),且治疗组明显低于对照组(P<0.05或P<0.01);治疗组妊娠率明显高于对照组,2组比较差异有统计意义(P<0.05)。结论 中西医结合促排卵治疗PCOS不孕症临床疗效确切,能够促进生殖内分泌激素的调整,从而提高患者的妊娠率。
Abstract:
Objective To explore the clinical effect of combined therapy of traditional Chinese and Western medicine by stimulating ovarian in treating infertility induced by polycystic ovary syndrome (PCOS). Methods 90 infertility patients with PCOS were randomly divided into control group and treatment group,45 cases in each group. The control group was treated with clomiphene citrate and human chorionic gonadotropin (CC/HCG). Based on that,the treatment group was intervened with traditional Chinese treatment additionally. The changes of luteinizing hormone,follicle stimulating,testosterone,estradiol before and after treatment as well as ovulation induction and pregnancy rate of the two groups after treatment were compared. Results The serum levels of luteinizing hormone in two groups were all decreased (P<0.05 or P<0.01),and the level in the treatment group decreased more than in the control group (P<0.05); the serum levels of testosterone and LH/FSH were decreased(P<0.05 or P<0.01),and the levels of the treatment group were lower than the control group(P<0.05 or P<0.01); the pregnancy rate in the treatment group was higher than that in the control group (P<0.05). Conclusion The combined therapy of traditional Chinese and Western medicine has good clinical effect in treating PCOS,promotes the adjustment of reproductive endocrine hormone and gets a better pregnancy rate.

参考文献/References:

[1] The Rotterdam ESHRE/ASRM-Sponsored PCOS Workshop Group.Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome[J].Fertil Steril,2004,81(1):19-25.
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[3] Larsen U.Research on interility:which definition should we use?[J].Fertil Steril,2005,83(4):846-852.
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备注/Memo

备注/Memo:
收稿日期:2015-08-07
基金项目:广东省中医药管理局资助项目(20131116)。
作者简介:王慧(1983-),女,主治中医师,医学硕士。研究方向:多囊卵巢综合征的中医药治疗。
更新日期/Last Update: 1900-01-01