[1]林瑞珠,朱宁,许建峰,等.回医烙灸疗法对激素性股骨头缺血性坏死家兔血流变、血脂及骨形态学的影响[J].甘肃中医药大学学报,2018,35(01):14-17.[doi:10.16841/j.issn1003-8450.2018.01.04]
 LIN Ruizhu,ZHU Ning,XU Jianfeng,et al.Effect of cauterization and moxibustion therapy in Hui Medicine on hemorheology,blood fat and bone morphology in rabbits with steroid induced avascular necrosis of the femoral head[J].Journal of Gansu University of Chinese Medicine,2018,35(01):14-17.[doi:10.16841/j.issn1003-8450.2018.01.04]
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回医烙灸疗法对激素性股骨头缺血性坏死家兔血流变、血脂及骨形态学的影响()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
35卷
期数:
2018年01期
页码:
14-17
栏目:
实验研究
出版日期:
2018-02-25

文章信息/Info

Title:
Effect of cauterization and moxibustion therapy in Hui Medicine on hemorheology,blood fat and bone morphology in rabbits with steroid induced avascular necrosis of the femoral head
作者:
林瑞珠13 朱宁1 许建峰23 刘剑1 马奇1 王月1 陈美华1
1. 宁夏医科大学总医院康复医学科, 宁夏 银川 750004;
2. 宁夏医科大学总医院中医骨伤科, 宁夏 银川 750004;
3. 宁夏医科大学回医药现代化教育部重点实验室, 宁夏 银川 750004
Author(s):
LIN Ruizhu13 ZHU Ning1 XU Jianfeng23 LIU Jian1 MA Qi1 WANG Yue1 CHEN Meihua1
1. Rehabilitation Medicine Department, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China;
2. TCM Orthopedics Department, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China;
3. Ministry of Education Key Laboratory for Modernization of Hui Medicine, Ningxia Medical University, Yinchuan, Ningxia, 750004, China
关键词:
激素性股骨头缺血性坏死回医烙灸疗法血液流变学总胆固醇三酰甘油骨形态学家兔实验研究
Keywords:
steroid induced avascular necrosis of the femoral headcauterization and moxibustion therapy in Hui MedicinehemorheologyTCTGbone morphologyrabbitexprimental study
分类号:
R-332
DOI:
10.16841/j.issn1003-8450.2018.01.04
摘要:
目的 研究回医烙灸疗法对激素性股骨头缺血性坏死(SANFH)家兔血流变、血脂及骨形态学的影响,从而探讨回医烙灸治疗SANFH的作用机制。方法 将24只家兔随机分为空白组、模型组、回医烙灸组,每组8只。使用糖皮质激素复制SANFH模型,回医烙灸组烙灸家兔肾俞穴和髋关节局部,空白组和模型组均不予任何干预。干预4周后进行血流变(包括全血高切、中切、低切黏度,血浆黏度,红细胞聚集指数,红细胞压积)、血脂[包括总胆固醇(TC)和三酰甘油(TG)]及骨形态学的观测和比较。结果 模型组家兔全血黏度、血浆黏度、红细胞聚集指数、TG、TC、空骨陷窝率较空白组明显升高(P<0.05或P<0.01),回医烙灸组以上指标均较模型组明显降低(P<0.05或P<0.01)。结论 回医烙灸疗法可以通过改善血液黏度、血脂,降低股骨头内空骨陷窝率,从而对早期SANFH产生一定的预防和治疗作用。
Abstract:
Objective To study the effect of cauterization and moxibustion therapy in Hui Medicine on hemorheology,blood fat and bone morphology in rabbits with steroid induced avascular necrosis of the femoral head (SANFH) and explore the mechanism of action treating SANFH.Methods 24 rabbits were randomly divided into control group,model group,cauterization and moxibustion group,8 in each. Glucocorticoids was used to establish SANFH models. The rabbit models were cauterized on the Shenshu (BL23) and part of hip joint. No intervention was allowed in control group and model group. After 4-week intervention,hemorheology (the high,medium and low whole blood viscosity,plasma viscosity,EAI,HCT),blood fat (TC,TG),bone morphology were observed and compared.Results Compared with control group,blood viscosity,plasma viscosity,red cell assembling index,TG,TC and percentage of empty lacunae in model group increased significantly (P<0.05 or P<0.01),which decreased notably in cauterization and moxibustion group (P<0.05 or P<0.01).Conclusion Cauterization and moxibustion therapy in Hui Medicine is effective in preventing and treating SANFH at early stage by regulating blood viscosity and blood fat,reducing percentage of empty lacunae.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2017-6-1。
基金项目:宁夏回族自治区自然基金项目(NZ15274)。
作者简介:林瑞珠(1979-),女,副主任医师,在读博士研究生,主要从事运动系统疾病的临床及基础研究。
更新日期/Last Update: 1900-01-01