[1]杜梦楠,张莹,孔凡铭,等.AZD9291致口腔炎1例[J].甘肃中医药大学学报,2018,35(01):74-76.[doi:10.16841/j.issn1003-8450.2018.01.20]
 DU Mengnan,ZHANG Ying,KONG Fanming,et al.One medical record of stomatitis induced by AZD9291[J].Journal of Gansu University of Chinese Medicine,2018,35(01):74-76.[doi:10.16841/j.issn1003-8450.2018.01.20]
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AZD9291致口腔炎1例()
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《甘肃中医药大学学报》[ISSN:1003-8450/CN:62-1062/R]

卷:
35卷
期数:
2018年01期
页码:
74-76
栏目:
药物不良反应
出版日期:
2018-02-25

文章信息/Info

Title:
One medical record of stomatitis induced by AZD9291
作者:
杜梦楠1 张莹2 孔凡铭2 张丽丽2 李文涛2
1. 天津中医药大学研究生院, 天津 300000;
2. 天津中医药大学第一附属医院肿瘤科, 天津 300000
Author(s):
DU Mengnan1 ZHANG Ying2 KONG Fanming2 ZHANG Lili2 LI Wentao2
1. Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 300000, China;
2. Oncology Department, First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300000, China
关键词:
AZD9291口腔炎药物不良反应个案
Keywords:
AZD9291stomatitisadverse drug reactioncase
分类号:
R979.1
DOI:
10.16841/j.issn1003-8450.2018.01.20
摘要:
通过AZD9291致口腔炎的个案报道,分析AZD9291致口腔炎的可能原因,探索预防该药致口腔炎的方法,为临床安全用药提供参考。
Abstract:
By exemplifying a medical record of stomatitis induced by AZD9291,the paper analyzes the possible causes and explores the measures of precaution,which provides reference for the safe medication in clinic.

参考文献/References:

[1] 何璐,钱研.Osimertinib治疗非小细胞肺癌的研究进展[J].中国新药与临床杂志,2016,12(6):398-404.
[2] Chia P L,John T.Vortex keratopathy presumed secondary to AZD9291[J].Journal of Thoracic Oncology,2015,10(12):1807-1808.
[3] Zhou W,Ercan D,Chen L,et al.Novel mutant-selective EGFR linase inhibitors against EGFR T790M[J].Nature,2009,462(7276):1070-1074.
[4] Yosaatmadja Y,Silva S,Dickson J M,et al.Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed[J].J Struct Biol,2015,192(3):539-544.
[5] 谢晓冬,郭放.EGFR-TKI相关皮肤毒性反应的研究现状及最新进展[C]//第八届全国癌症康复与姑息医学大会论文汇编.青岛:中国抗癌协会癌症康复与姑息治疗专业委员会(CRPC),2012:6.
[6] Woodwoth C D,Michael E,Marker D,et al,Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation apoptosis and cell attachment[J].Mol Cancer Ther,2005,4(4):650-658.
[7] 林如衡.常见口腔炎的诊断和治疗[J].中级医刊,2006(22):518-522.

备注/Memo

备注/Memo:
收稿日期:2017-4-14。
基金项目:国家自然科学基金青年基金项目(81403220)。
作者简介:杜梦楠(1991-),男,在读硕士研究生。研究方向:中医内科学肿瘤方向。
通信作者:张莹(1977-),女,副主任医师,医学硕士。研究方向:中医内科学肿瘤方向。E-mail:zhangyingzhongyi@sina.com
更新日期/Last Update: 1900-01-01