PDF下载 分享
[1]臧凯宏,李应东,朱丽娟,等.黄芪多糖对溃疡性结肠炎大鼠结肠黏膜的修复作用及其作用机制研究[J].甘肃中医药大学学报,2018,35(03):5-10.[doi:10.16841/j.issn1003-8450.2018.03.02]
 ZANG Kaihong,LI Yingdong,ZHU Lijuan,et al.Study on the repair effect on colon mucosa and mechanism of astragalus polysaccharides in rats with ulcerative colitis[J].Journal of Gansu University of Chinese Medicine,2018,35(03):5-10.[doi:10.16841/j.issn1003-8450.2018.03.02]
点击复制

黄芪多糖对溃疡性结肠炎大鼠结肠黏膜的修复作用及其作用机制研究

参考文献/References:

[1] Neurath M.Current and emerging therapeutic targets for IBD[J].Nature Reviews Gastroenterology & Hepatology,2017,14(5):269-278.
[2] Zmora N,Levy M,Pevsner-Fishcer M,et al.Inflammasomes and intestinal inflammation[J].Mucosal Immunology,2017,10(4):865-883.
[3] 张俊,王朋川,李贵轲,等.溃疡性结肠炎肠黏膜屏障损伤机制的研究进展[J].广州化工,2017(8):28-30.
[4] Lechuga S,Ivanov A I.Disruption of the epithelial barrier during intestinal inflammation:quest for new molecules and mechanisms[J].Biochimica Et Biophysica Acta-Molecular Cell Research,2017(7):1183-1194.
[5] Sánchez de Medina F,Romero-Calvo I,Mascaraque C,et al.Intestinal inflammation and mucosal barrier function[J].Inflammatory Bowel Diseases,2014,20(12):2394-2404.
[6] 刘元艳,刘学文,谭勇,等.基于文本挖掘探索溃疡性结肠炎药物的治疗规律[J].中国实验方剂学杂志,2013(15):329-332.
[7] 贺海辉,沈洪,朱宣宣,等.黄芪对三硝基苯磺酸诱导的大鼠结肠炎的作用[J].中华中医药杂志,2013(10):3082-3085.
[8] 常慧芳.黄芪仙鹤草汤治疗溃疡性结肠炎的临床特点及疗效观察[J].世界最新医学信息文摘,2016(51):156-157.
[9] 臧凯宏,吴建军,秦红岩,等.黄芪多糖对溃疡性结肠炎大鼠肠道黏膜屏障的影响[J].中药材,2017(1):208-211.
[10] Morris G P,Beck P L,Herridge M S,et al.Hapten-induced model of chronic inflammation and ulceration in the rat colon[J].Gastroenterology,1989,96(3):795-803.
[11] Leppkes M,Roulis M,Neurath M F,et al.Pleiotropic functions of TNF-alpha in the regulation of the intestinal epithelial response to inflammation[J].International Immunology,2014,26(9):509-515.
[12] Vizio B,Poli G,Chiarpotto E,et al.4-Hydroxynonenal and TGF-beta1 concur in inducing antiproliferative effects on the CaCo-2 human colon adenocarcinoma cell line[J].Biofactors,2005,24(1/4):237-246.

相似文献/References:

[1]曾松,何永恒.白芍七物颗粒对溃疡性结肠炎大鼠血小板和血清一氧化氮的影响[J].甘肃中医药大学学报,2015,32(03):10.
 ZENG Song,HE Yongheng.Effects of Baishao Qiwu Granule on platelet and serum nitric oxide in rats with ulcerative colitis[J].Journal of Gansu University of Chinese Medicine,2015,32(03):10.
[2]赵新芳,甘霞,林红,等.溃疡性结肠炎病变部位、活动性与中医辨证分型关系的研究[J].甘肃中医药大学学报,2015,32(05):32.
 ZHAO Xinfang,GAN Xia,LIN Hong,et al.Study on the correlation of diseased regions,activity and TCM syndromes of ulcerative colitis[J].Journal of Gansu University of Chinese Medicine,2015,32(03):32.
[3]王吉娥,徐萌,黄秀深,等.中医药抗溃疡性结肠炎的临床及实验研究概况[J].甘肃中医药大学学报,2015,32(05):53.
[4]吴红彦,李海龙,吴国泰,等.石榴健胃片对脾肾阳虚型溃疡性结肠炎模型大鼠结肠炎症因子的影响[J].甘肃中医药大学学报,2016,33(01):9.[doi:10.16841/j.issn1003-8450.2016.01.03]
 WU Hongyan,LI Hailong,WU Guotai,et al.Effects of Shiliu Jianwei Tablet on inflammatory factors in the model rats with ulcerative colitis due to yang-deficiency of spleen and kidney[J].Journal of Gansu University of Chinese Medicine,2016,33(03):9.[doi:10.16841/j.issn1003-8450.2016.01.03]
[5]侯高.溃疡性结肠炎诊治体会[J].甘肃中医药大学学报,1997,(02):38.
[6]杨德全,强志明.桃叶合剂灌肠治疗溃疡性结肠炎72例[J].甘肃中医药大学学报,1998,(01):26.
[7]刘荣汉.长嘴老鹳草治疗溃疡性结肠炎67例临床观察[J].甘肃中医药大学学报,2005,(02):25.
 Liu Ronghan.Geranium wilfordii Maxim for ulcerative colitis:a clinical observation of 67 cases[J].Journal of Gansu University of Chinese Medicine,2005,(03):25.
[8]徐淑琴,金权,张思胜.中西医结合治疗慢性非特异性溃疡性结肠炎56例[J].甘肃中医药大学学报,2005,(05):31.
[9]邓华栋.加味薏苡附子败酱散内服合西药灌肠治疗溃疡性结肠炎[J].甘肃中医药大学学报,2007,(01):23.
[10]段永强,梁玉杰,程容,等.痛泻二草方对肝郁脾虚型UC模型大鼠肠黏膜屏障损伤的影响[J].甘肃中医药大学学报,2007,(05):3.
 Duan Yongqiang,Liang Yujie,Cheng Rong,et al.Effects of Tongxie Ercao Fang on barrier loss of intestinal mucosa in rats with ulcerative colitis of stagnation of liver-qi and deficiency of the spleen[J].Journal of Gansu University of Chinese Medicine,2007,(03):3.

备注/Memo

收稿日期:2017-09-01。
基金项目:甘肃省自然科学基金项目(1606RJZA062);甘肃省中医药防治慢性疾病重点实验室开放基金项目(GSMBKY2015-10,GSMBKY2015-11);甘肃中医药大学中青年科研基金项目(ZQ2015-13)。
作者简介:臧凯宏(1975-),男,讲师,医学硕士。研究方向:炎症性肠病发病机制及药物治疗。
通信作者:吴建军(1972-),男,副教授,医学博士,主要从事中医药防治慢性病的研究。E-mail:wjj@gszy.edu.cn

更新日期/Last Update: 1900-01-01